Pilot study of combined therapy with interferon-alpha, arabinosyl cytosine and all-trans retinoic acid in patients with chronic myeloid leukemia in the chronic phase.

1. Pietrangelo A, Camaschella C. Molecular genetics and control of iron metabolism in hemochromatosis. Haematologica 1998; 83:456-61. 2. Feder JN, Gnirke A, Thomas W, et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996; 13:399-408. 3. Crawford DG, Powell LW, Leggett BA, et al. Evidence that the ancestral haplotype in Australian hemochromatosis patients may be associated with a common mutation in the gene. Am J Hum Genet 1995; 57:3627. 4. Piperno A, Arosio C, Fargion S, et al. The ancestral hemochromatosis haplotype is associated with a severe phenotype expression in Italian patients. Hepatology 1996; 24:43-6. 5. Piperno A, Sampietro M, Pietrangelo A, et al. Heterogeneity of hemochromatosis in Italy. Gastroenterol 1998; 114:996-1002. 6. Adams PC, Valberg LS. Evolving expression of hereditary hemochromatosis. Semin Liv Dis 1996; 15:47-54. 7. Jazwinska EC, M Cullen L, Busfield F, et al. Haemochromatosis and HLA-H. Nature Genet 1996; 14:24950. 8. Totaro A, Roetto A, Rommens JM, et al. Generation of a transcription map of a 1 Mbase region containing the HLA-H gene on 6p22. Eur J Hum Genet 1998; 6:105-13. 9. Porto G, Vicente C, Teixeira MA, et al. Relative impact of HLA phenotype and CD4-CD8 ratios on the clinical expression of hemochromatosis. Hepatology 1997; 25:397-402. 10. Camaschella C, Roetto A, Piperno A, et al. Allelic association of microsatellite of 6p in Italian hemocromatosis patients. Hum Genet 1996; 97:476-81.